ACE Activities Reports
Selected Publications
African Centers of Excellence in Bioinformatics and Data Intensive Science: Building capacity for enhancing data intensive infectious diseases research in Africa
Giovanni MY, Whalen C, Hurt DE, Ware-Allen L, Noble K, McCarthy M, Quinones M, Cruz P, Jjingo D, Wele M, Doumbia S, Tartakovsky M. Journal of Infectious Diseases & Microbiology. 2022.
Machine learning-based prediction of antibiotic resistance in Mycobacterium tuberculosis clinical isolates from Uganda
Babirye SR, Nsubuga M, Mboowa G, Batte C, Galiwango R, Kateete DP. BMC Infectious Diseases. 2024.
Pf Phosphatidylserine decarboxylase: Molecular modeling and inhibitors prediction
Sangare M, Risse C, Cruz P, Diabate O, Shaffer JG, Li J, Doumbia S, Wele M. Research & Reviews: Journal of Computational Biology. 2024.
Psychological distress among ethnically diverse participants from Eastern and Southern Africa
Tindi et al. JAMA Network Open. 2024.
Research ethics and artificial intelligence for global health: perspectives from the global forum on bioethics in research
Shaw J, Ali J, Atuire CA, Cheah PY, Español AG, Gichoya JW, Hunt A, Jjingo D, Littler K, Paolotti D, Vayena E. BMC Medical Ethics. 2024.
Structural insights into conformational stability of both wild-type and mutant Insulin Receptor Gene
Soremekun C, Jjingo D, Kateete D, Nash O, Grallert H, Peters A, Chikowore T, Batini C, Soremekun O, Fatumo S. Next Research. 2024.
The dawn of a cure for sickle cell disease through CRISPR-based treatment: A critical test of equity in public health genomics
Mboowa G, Sserwadda I, Kanyerezi S, Tukwasibwe S, Kidenya B. Annals of Human Genetics. 2024.
The rise of pathogen genomics in Africa
Mboowa G, Kakooza F, Egesa M, Tukwasibwe S, Kanyerezi S, Sserwadda I, R Kidenya B, Kabahita JM, Namaganda MM, Nsubuga M, Nabisubi P, Ayitewala A, Kebirungi G, Nakafu E, Akwii NP. F1000 Research. 2024.
The Ugandan sickle Pan-African research consortium registry: design, development, and lessons
Nsubuga M, Mutegeki H, Jjingo D, Munube D, Namazzi R, Opoka R, Kasirye P, Ndeezi G, Hume H, Mupere E, Kebirungi G, Birungi I, Morrice J, Jonas M, Nembaware V, Wonkam A, Makani J, Kiguli S. The Ugandan sickle Pan-African research consortium registry: design, development, and lessons. BMC Medical Informatics & Decision Making. 2024.
Virtual reality technology for surgical learning: qualitative outcomes of the first virtual reality training course for emergency and essential surgery delivered by a UK–Uganda partnership
Please H, Narang K, Bolton W, Nsubuga M, Luweesi H, Richards NB, Dalton J, Tendo C, Khan M, Jjingo D, Bhutta MF, Petrakaki D, Dhanda J. BMJ Open Quality. 2024.
A Mendelian randomization study of genetic liability to post-traumatic stress disorder and risk of ischemic stroke
Soremekun O, Musanabaganwa C, Uwineza A, Ardissino M, Rajasundaram S, Wani AH, Jansen S, Mutabaruka J, Rutembesa E, Soremekun C, Cheickna C, Wele M, Mugisha J, Nash O, Kinyanda E, Nitsch D, Fornage M, Chikowore T, Gill D, Wildman DE, Mutesa L, Uddin M, Fatumo S. Translational Psychiatry. 2023.
Genome-wide association analysis of cystatin-C kidney function in continental Africa
Mayanja R, Machipisa T, Soremekun O, Kamiza AB, Kintu C, Kalungi A, Kalyesubula R, Sande OJ, Jjingo D, Fabian J, Robinson-Cohen C, Franceschini N, Nitsch D, Nyirenda M, Zeggini E, Morris AP, Chikowore T, Fatumo S. eBioMedicine. 2023.
Killer cell immunoglobulin receptor diversity and its relevance in the human host’s response to HIV infection in African populations
Mukisa J, Amujal M, Sande OJ, Joloba ML, Jjingo D, Kateete DP, Mardon G, Matshaba M, Hanchard N, Hollenbach JA. Translational Medicine Communications. 2023.
Meta-analysis and multivariate GWAS analyses in 77,850 individuals of African ancestry identify novel variants associated with blood pressure traits
Udosen B, Soremekun O, Kamiza A, Machipisa T, Cheickna C, Omotuyi O, Soliman M, Wélé M, Nashiru O, Chikowore T, Fatumo S. International Journal of Molecular Sciences. 2023.
Meta-analysis of African ancestry genome-wide association studies identified novel locus and validates multiple loci associated with kidney function
Kintu C, Soremekun O, Machipisa T, Mayanja R, Kalyesubula R, Bagaya BS, Jjingo D, Chikowore T, Fatumo S. BMC Genomics. 2023.
Multi-trait discovery and fine-mapping of lipid loci in 125,000 individuals of African ancestry
Kamiza AB, Touré SM, Zhou F, Soremekun O, Cissé C, Wélé M, Touré AM, Nashiru O, Corpas M, Nyirenda M, Crampin A, Shaffer J, Doumbia S, Zeggini E, Morris AP, Asimit JL, Chikowore T, Fatumo S. Nature Communications. 2023.
No association of a Vascular endothelial growth factor A (VEGFA) gene polymorphism with pre-eclampsia among pregnant women in Uganda
Nabweyambo S, Kanyerezi S, Petterson JH, Katabazi FA, Ssekagiri A, Mwesigwa S, Mboowa G, Nakazzi F, Keesiga A, Adroma M, Bwanga F, McGovern N, Sande OJ, Nakimuli A. BMC Genomics. 2023
Phylogenomic analysis uncovers a 9-year variation of Uganda influenza type-A strains from the WHO-recommended vaccines and other Africa strains
Nabakooza G, Owuor DC, de Laurent ZR, Galiwango R, Owor N, Kayiwa JT, Jjingo D, Agoti CN, Nokes DJ, Kateete DP, Kitayimbwa JM, Frost SDW, Lutwama JJ. Scientific Reports. 2023.
Sputum microbiome and chronic obstructive pulmonary disease in a rural Ugandan cohort of well-controlled HIV infection
Kayongo A, Bartolomaeus TUP, Birkner T, Markó L, Löber U, Kigozi E, Atugonza C, Munana R, Mawanda D, Sekibira R, Uwimaana E, Alupo P, Kalyesubula R, Knauf F, Siddharthan T, Bagaya BS, Kateete DP, Joloba ML, Sewankambo NK, Jjingo D, Kirenga B, Checkley W, Forslund SK. Microbiology Spectrum. 2023.
The causal effects of lipid traits on kidney function in Africans: bidirectional and multivariable Mendelian-randomization study
Kintu C, Soremekun O, Kamiza AB, Kalungi A, Mayanja R, Kalyesubula R, Bagaya S B, Jjingo D, Fabian J, Gill D, Nyirenda M, Nitsch D, Chikowore T, Fatumo S. eBioMedicine. 2023.
Type 2 diabetes prevalence, awareness, and risk factors in rural Mali: a cross-sectional study
Diawara A, Coulibaly DM, Hussain TYA, Cisse C, Li J, Wele M, Diakite M, Traore K, Doumbia SO, Shaffer JG. Scientific Reports. 2023.
Unraveling virulence determinants in extended-spectrum beta-lactamase-producing Escherichia coli from East Africa using whole-genome sequencing
Sserwadda I, Kidenya BR, Kanyerezi S, Akaro IL, Mkinze B, Mshana SE, Hashim SO, Isoe E, Seni J, Joloba ML, Mboowa G. BMC Infectious Diseases. 2023.
Bioinformatics mentorship in a resource limited setting
Jjingo D, Mboowa G, Sserwadda I, Kakaire R, Kiberu D, Amujal M, Galiwango R, Kateete D, Joloba M, Whalen CC. Briefings in Bioinformatics. 2022.
Feasibility of virtual reality-based training for optimizing COVID-19 case handling in Uganda
Buyego P, Katwesigye E, Kebirungi G, Nsubuga M, Nakyejwe S, Cruz P, McCarthy MC, Hurt D, Kambugu A, Arinaitwe JW, Ssekabira U, Jjingo D. BMC Medical Education. 2022.
First report of whole-genome analysis of an extensively drug-resistant Mycobacterium tuberculosis clinical isolate with bedaquiline, linezolid and clofazimine resistance from Uganda
Kabahita JM, Kabugo J, Kakooza F, Adam I, Guido O, Byabajungu H, Namutebi J, Namaganda MM, Lutaaya P, Otim J, Kakembo FE, Kanyerezi S, Nabisubi P, Sserwadda I, Kasule GW, Nakato H, Musisi K, Oola D, Joloba ML, Mboowa G. Antimicrobial Resistance & Infection Control. 2022.
Genetic diversity, distribution, and genomic characterization of antibiotic resistance and virulence of clinical Pseudomonas aeruginosa strains in Kenya
Kiyaga S, Kyany'a C, Muraya AW, Smith HJ, Mills EG, Kibet C, Mboowa G, Musila L. Frontiers in Microbiology. 2022.
Molecular epidemiology and evolutionary dynamics of human influenza type-A viruses in Africa: A systematic review
Nabakooza G, Galiwango R, Frost SDW, Kateete DP, Kitayimbwa JM. Microorganisms. 2022.
Molecular dynamic simulation reveals structure differences in APOL1 variants and implication in pathogenesis of chronic kidney disease
Mayanja R, Kintu C, Diabate O, Soremekun O, Oluwagbemi OO, Wele M, Kalyesubula R, Jjingo D, Chikowore T, Fatumo S. Genes (Basel). 2022.
QuasiFlow: a Nextflow pipeline for analysis of NGS-based HIV-1 drug resistance data
Ssekagiri A, Jjingo D, Lujumba I, Bbosa N, Bugembe DL, Kateete DP, Jordan IK, Kaleebu P, Ssemwanga D. Bioinformatics Advances. 2022.
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
Tegally et al. Science. 2022.